Endocrine Abstracts

In laboratories employing 'front-line' sensitive TSH measurement, it is generally accepted that fully suppressed TSH levels (3rd generation assays) alongside normal free thyroid hormone levels indicate subclinical hyperthyroidism. However, low but not suppressed levels are often labelled as non-thyroidal illness.We investigated 25 successive ambulant individuals, identified over an 18 month period as having low but not fully suppressed TSH levels (3rd ge...

Introduction: Overfeeding adolescent ewes with singleton pregnancies results in reduced placental size and low lamb birth weight at term. We have investigated if reduced placental size is associated with altered placental cell proliferation and apoptosis at day 80 of pregnancy (peak placental growth period). Methods: Singleton pregnancies to a single sire were established by embryo transfer to adolescent recipient dams. Pregnant ewes were offered high (H, n = 14) or moderate (...